Develop and execute strategies to service and increase financial support for teach for Pakistan?s operations ??? Develop and/or support wider communication that raises awareness of teach for Pakistan?s mission and work
Qualifications: ??? Bachelor?s degree required, Masters Preferred ??? At least 5-7 years of work experience in fund raising, marketing and media relations
The salary package for each position will depend upon individual qualifications and experience.
For complete job descriptions and further information on how to apply. Please visit http://teachforpakistan.edu.pk/website/careers.
The final date to submit applications is January 13, 2013.
UFC 155: Dos Santos vs. Velasquez 2 is taking place at the MGM Grand Garden Arena in Las Vegas, NV.
Follow the live results below:
Main Card (PPV): -Junior dos Santos (15-1) vs. Cain Velasquez (10-1) -Jim Miller (21-4) vs. Joe Lauzon (22-7) -Tim Boetsch (16-4) vs. Constantinos Philippou (11-2) -Yushin Okami def. Alan Belcher via unanimous decision (30-27, 30-27, 29-28) -Derek Brunson def. Chris Leben via unanimous decision (29-28, 29-28, 29-28)
Preliminary Card (FX): -Eddie Wineland def. Brad Pickett via split decision (30-27, 28-29, 30-27) -Erik Perez def. Byron Bloodworth via TKO (strikes) at 3:50, Round 1 -Melvin Guillard def. Jamie Varner via unanimous decision (30-27, 27-30, 30-27) -Myles Jury def. Michael Johnson via unanimous decision (30-27, 30-27, 30-27)
Preliminary Card (Facebook): -Todd Duffee vs. Phil De Fries via TKO (punches) at 2:04, Round 1 -Max Holloway def. Leonard Garcia via split decision (29-28, 28-29, 29-28) -John Moraga def. Chris Cariaso via submission (guillotine choke) at 1:11, Round 3
67 WALL STREET, New York - December 20, 2012 - The Wall Street Transcript has just published its Gold and Precious Metals Report offering a timely review of the sector to serious investors and industry executives. This special feature contains expert industry commentary through in-depth interviews with public company CEOs, Equity Analysts and Money Managers. The full issue is available by calling (212) 952-7433 or via The Wall Street Transcript Online.
Topics covered: Investment and Central Bank Demand - Gold Producers vs. Gold ETF - Midcap and Small-Cap Consolidation Activity - The Rise of Gold ETFs - Central Banks as Net Buyers of Gold
Companies include:Goldcorp Inc. (GG), Gold Fields Ltd. (GFI) and many others.
In the following excerpt from the Gold and Precious Metals Report, an experienced portfolio manager discusses his investment methodology:
TWST: In general, how would you describe your investment strategy as it pertains to the OCM Gold Fund?
Mr. Orrell: Our first approach always comes from the macro standpoint of where we believe gold is going - what's gold doing? And then, we go from there to the individual issues. So looking at mostly in the mining stocks, we are predominantly in the gold miners, and we have what we call a tiered approach of having positions in major producers and immediate junior producers, and the exploration and development companies. And then, that percentage allocation in each group changes depending on our view of where we believe the value is. Further, we do believe that capital flows do run down to each segment, depending on where you are in various cycles in the gold market at that moment. So we like to have companies that are exhibiting strong fundamentals, from cash flow generation to reserve replacement to reserves per share, and we also are looking for companies that can create value through the drill bit.
TWST: Would you elaborate a little bit about the characteristics you're looking for in a gold mining company? And conversely, what would make a gold mining company an unattractive investment in your mind?
Mr. Orrell: What we're looking for are companies that are showing discipline. On the larger side, we're looking for companies that are showing a discipline in terms of their capital deployment, and that they're holding equity dear. That has certainly been an issue. Mining companies that have become serial issuers of equity; that's not what we're looking for. We know that it is a capital-intensive business, but there has to be a measured approach. So the companies that we focus on in our portfolio are companies that have exhibited an ability to manage their business in terms of doing what they say they are going to do - replacing reserves while also looking to grow their production portfolio with higher-quality assets. Basically, that's what we're looking for.
Conversely, companies that we're shying away from are companies that have exhibited a poor track record of execution - from reserve replacement to capital deployment. We avoid companies that are not investor friendly from the standpoint of realizing that shareholders need to see a return on equity through dividends. Companies that do put the shareholder high on that priority list, and that there is going to be a call on a portion of the cash flow from each operation because the mining business is a depleting resource business and the shareholders need to participate in each operation - we want companies where the management sees that. Otherwise, it's a fool's game for the investor where the only winners are engineers, geologists, suppliers and the tax man.
TWST: Would you give us three examples of gold mining companies currently in the fund and tell us what you like about each of them?
For more of this interview and many others visit the Wall Street Transcript - a unique service for investors and industry researchers - providing fresh commentary and insight through verbatim interviews with CEOs, portfolio managers and research analysts. This special issue is available by calling (212) 952-7433 or via The Wall Street Transcript Online.
Recreation-and-Sports moncler Learning to make Softball Workouts for Reaching, Fielding, and Tossing moncler Powerful
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Je viens de me remettre au d?veloppement apr?s 20 ans de pause. J'ai fabriqu? une petite appli pour entra?ner les enfants ? ne pas confondre certaines consonnes (je suis orthophoniste), avec une version payante et une d?mo gratuite. J'aurais deux questions ? poser aux habitu?s que vous ?tes :
1) Quand j'ai mis en ligne la version 1.1, pendant quelques heures, personne ne pouvait t?l?charger mon appli, alors que j'?tais en train d'en discuter arler sur des forums. Apparemment j'aurais d? laisser la v1.0 active et attendre un peu. Mais attendre quoi, et combien de temps ? Du coup, j'h?site ? mettre en ligne les am?liorations que j'ai encore apport?es depuis. Je crains que l'appli soit ? nouveau inaccessible.
2) J'ai mis en ligne la version gratuite hier, vers 17h. Il est 9h, pr?sentement, et je ne vois toujours que la version payante sur Google Play. Est-ce normal ? Savez-vous si les applications sont v?rifi?es par des gens qui travaillent en France, ou si on doit jongler avec le d?calage horaire ?
Ce manque de r?activit? m'?tonne, mais je suis probablement trop impatient...
SAN FRANCISCO ? Google Inc. said several of its online services have been blocked in China.
Traffic to Google?s services in China dropped sharply beginning Friday evening there, according to an online ?Transparency Report? website operated by Google, which provides updates about access to its services in different parts of the world.
Among the sites affected were Google?s search engine and its Gmail web email product.
The disruptions come as China?s government kicked off the 18th Chinese Communist Party Congress this week to appoint a new generation of leaders. The country maintains media regulations that let it block websites that it deems out of compliance with those rules.
A Google spokeswoman said the company did not know why the disruption was happening. Google said in a statement that it had ?checked and there?s nothing wrong on our end.?
Ma Yuanchun, a spokeswoman for the Chinese consulate in New York, said she wasn?t informed on the matter and referred all queries to the relevant government authorities in Beijing. Calls and an e-mail sent after normal office hours to Hong Lei, a spokesman at the Chinese foreign ministry in Beijing, weren?t immediately answered.
Google?s YouTube video service has been inaccessible in China since 2009, while access to other services in China are blocked sporadically.
In 2010 Google relocated its Chinese search engine to Hong Kong after a spat with authorities over censorship and cyber-attacks that Google said originated in China. Hong Kong isn?t subject to Web restrictions imposed in mainland China.
Google rose 1.6% to US$662.69 at 1:33 p.m. in New York. The shares are up about 1% this year through yesterday.
Being poor and being a student go hand-in-hand. Students do not need to resort to selling plasma to earn extra money. With a bit of creativity, they can save money without making any sacrifices. They may even have enough extra to spend at the local pub. If you are in school, follow these tips to save yourself some money so you can enjoy everything that higher education has to offer. Just do not enjoy life too much or you may find yourself without a degree!
The 16-25 Railcard is perfect for full-time students and is available for one or three years. It features a one-third discount on railway travel across the UK. Cardholders also receive access to partnership contests and offers like holiday discounts and reduced prices for West-End theatre tickets. Cost of a one-year card is currently ?28 and a three-year card sells for ?65. Students who travel in groups may be able to secure group discounts like three or four adults traveling for the price of two.
The license fee terms from the BBC require consumers to pay the fee if they view or record television as it is broadcast. However, a license is not required for watching television on-demand online. Students can purchase a cable to connect their laptops to their televisions to view at no charge. Those who do pay for a license should request a refund for the summer months that they are not in their homes. The extra money can be spent on groceries.
It?s Easier Than It Looks To Save Money
When food shopping, students should buy in bulk and cook from scratch rather than purchasing ready-made meals. Pasta has a long shelf-life and makes an inexpensive meal for a flat full of students. Those who spend time shopping for other household items should take their NUS extra card and university card with them.
A store that does not participate in NUS may offer separate discounts. Specialized student discount sites like Studentbeans offer free memberships.
It can be expensive to print papers and other homework assignments on campus. Students should consider purchasing a printer to print their work at home. They will save themselves the stress of having to wait in long lines to print at campus and can even make money during the third year of school when everyone is printing dissertations.
Students who enjoy shopping for clothes and accessories can save money by working where they shop. Arcadia Group offers a 25 percent discount to employees of Topshop, Miss Selfridges, Topman, and its other stores and 20 percent off at BHS. Employees of New Look, The Body Shop, and Republic receive up to 50 percent off their purchases.
Freecycle is a great place for students to find free items like bicycles, televisions, and laptops. Charity shops offer books, CDs, DVDs, clothing, and accessories at low prices and there seem to be a few of these on most high streets. Car boot sales are weather-dependent but often include hidden treasures. Students should plan to be there bright and early to find the best deals.
A Canadian University Student Shares Her Money-Saving Ideas
Martin Lewis? Discusses Student Finance In?2012 And Beyond
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Forensic scientists may have a new tool to analyze suspicious fibers from crime scenes. The mass spectrometry method identifies dyes on nylon, a common carpet material (Anal. Chem., DOI: 10.1021/ac3025569).
The technique could provide backup for existing forensic fiber analysis techniques, allowing investigators to compare fibers from crime scenes with those associated with suspects. This new method also consumes a very small amount of the evidence, says David Hinks, a textile chemist at North Carolina State University, who developed the method with chemist Chuanzhen Zhou and others.
?Sometimes you get very little evidence from a crime scene. We want to minimize destruction of fiber evidence, especially when it is trace evidence,? Zhou says.
With funding from the National Institute of Justice, the team developed the method, which involves first cleaning residues off the fiber?s surface using a beam of ionized C60 fullerenes. Then the researchers use time-of-flight secondary ion mass spectrometry (TOF-SIMS) to analyze the chemical fingerprint of the dye, fiber, and any trace chemicals on the fiber?s surface.
Most forensic labs currently employ polarized light microscopy to identify fibers. Some labs then extract the dye from the fiber and analyze it by thin-layer chromatography, Hinks says.
By analyzing fiber and dye at the same time with the new technique, researchers can also identify trace contaminants in the material from its industrial production process. Identifying these compounds could give investigators an idea of which company produced a particular piece of material, which would then improve the accuracy of comparisons of fibers found at a crime scene to ones from a suspect, he says.
?I?d like to see this applied to a real forensic case,? comments University of Manchester mass spectrometry expert John Vickerman. He agrees that TOF-SIMS could be useful for forensic scientists. ?They?ve shown what might be possible, but it is not yet a proof of principle for all cases,? he adds.
?Many forensic and conservation scientists shy away from using these ?destructive techniques? because they consume a small amount of the specimen,? he says. However, this work, he adds, ?clearly demonstrates that the amount of accurate information obtained from these techniques justifies their minimally destructive nature.?
The North Carolina State team is now extending the method to polyester and cotton.
Begins now your journey young Padawan. ?You must teach your birds to fly with the power of the force and defeat the Pigtroopers?of the Dark Lord Pig Vader. Yes, Angry Birds Star Wars is finally here for mobile devices from planet Earth to a galaxy far far away.
Read more: Clear Your Mind Must Be for #AngryBirdsStarWars Has Arrived
All Critics (113) | Top Critics (37) | Fresh (107) | Rotten (6)
Forced to do all his acting with his face, Hawkes displays the kind of camera-arresting capability that has earned others Oscar nominations.
This is a crowd-pleaser of the finest sort.
Using only his tilted head, his eyes, nose, and mouth and that quizzical voice, Hawkes brings O'Brien to life.
It's funny and well-meaning, with great performances, but the story plays out more like an Afterschool Special with full-frontal nudity.
Most often with The Sessions the blunt comedy outweighs the drift toward sanctimony.
An extraordinary account of sexual exploration and intimacy against the odds, The Sessions is a powerful achievement.
Sex & a very singular man
Boasts a rare, inherent understanding of its subject, with Lewin now facing the prospect of becoming seriously hot property, as awards season beckons.
We are engaged by the compelling characters and a man's discovery of sexuality in a short span of time and in a unique way. And we are touched by the relationship that develops
Sex, religion, poetry and the disabled might be the subject matter, but nothing will prepare you for the emotions that are shared in this unique, poignant and unforgettable film
The most grown-up depiction of emotionally meaningful sexual relations... that will have any sort of general distribution in U.S. movie theaters in this or any of the next several years.
The Sessions resembles one of O'Brien's poems (which are featured in the story) - neither flawless nor ever-graceful in terms of technique but still gentle and sincere.
A dramatic, inspiring story that can be humorous at times with endearing characters. This is a crowd-pleaser that is sure to be a contender at the Oscars.
[ The Sessions] is very sweet and heartfelt, but never cloying or overly sentimental.
The Sessions is a truly inspirational work, grounded by a powerful, thought-provoking performance that lingers long after one has left the auditorium. It is one of the more memorable, if imperfect, achievements of 2012.
It's really a three-character comedy/drama, with the best elements of both genres.
"The Sessions" shapes its themes in an appealing way and keeps the script lively and engaging and funny.
This isn't the first film to explore the subject of the sexuality of the disabled. But it is, thanks to sensitive direction from Ben Lewin and empathetic performances that never condescend, among the best.
A remarkable story of bravery and compassion
With its assertive hero and inclusive humor, "The Sessions" is an inspirational drama you can feel good about in the morning.
Gets it right, in the essence of its true story as well as the social discomforts surrounding disability and sane discussion of sexuality.
Brad Maddox discusses his big match with Ryback next week: WWE.com Exclusive, Nov. 5, 20123MB comments on Drew McIntyre's whereabouts: WWE.com Exclusive, Nov. 5, 2012John Cena & Ryback vs. CM Punk & Dolph Ziggler: Raw, Nov. 5, 2012Brodus Clay vs. Wade Barrett: Raw, Nov. 5, 2012Jey Uso vs. Heath Slater: Raw, Nov. 5, 2012Kofi Kingston comments on being part of Team Foley: WWE.com Exclusive, Nov. 5, 2012WWE Official Rod Zapata comments on Brad Maddox: WWE.com Exclusive, Nov. 5, 2012
An opportunity like the one Mr. McMahon granted to Brad Maddox on Raw comes along once in a million lifetimes. Many members of the WWE Universe and Superstars in the locker room might be wondering why the "Hell" Maddox deserves it.
(MORE: WHO IS BRAD MADDOX??| PHOTOS FROM HELL IN A CELL)
On next week's Raw, the developmental talent turned WWE referee will step into the ring to face Ryback with a million-dollar WWE contract hanging in the balance. That's right ? the same man responsible for the most heinous attack by a WWE official ever gets the chance to achieve his lifelong dream of becoming a Superstar if he can win just one match.
OK, we know what you're thinking: Ryback is going to tear this rogue ref apart like a turkey leg at Thanksgiving. You can imagine the punishment Ryback will inflict on the person responsible for ending his undefeated streak and costing him a potential WWE Championship victory inside Hell in a Cell. Does Maddox even stand a remote chance of making the nearly 300-pound juggernaut wince in pain, let alone pinning his shoulders to the canvas for a three-count?
Regardless of Maddox's long odds next week, however, one has to question the path which led him to such an extremely rare opportunity. Following his controversial actions at WWE Hell in a Cell and subsequent questioning by WWE's Board of Inquiry, Maddox finally decided to explain his blatant interference during the WWE Title Match to the entire WWE Universe on Raw (VIDEO?| PHOTOS). But instead of expressing remorse for the uproar he had caused, the disgraced official sounded ever so boastful about his plan ? one that he confessed was his alone ? to finally get noticed in WWE after struggling to get his foot in the door for years.
"I made an impact," Maddox said on Raw. "My actions, very simply, were driven by my desire to be somebody. Well, I'm somebody now! People know my name everywhere!"
The defiant Maddox then proceeded to demand a WWE contract and a match against Ryback ? two wishes that Mr. McMahon promptly fulfilled.
Is it fair that Maddox's attention-grabbing stunt and whiny speech led him closer to breaking through as a WWE Superstar? Or is The Chairman hoping a brutal defeat to Ryback will be exactly what breaks Maddox's spirit for good ? fitting discipline for his unforgivable attack at WWE Hell in a Cell?
Next Monday, Maddox might severely regret the night he ever crossed Ryback. But maybe, just maybe, he could pull off one of the greatest upsets in history and seize that coveted WWE contract. If the latter somehow comes to pass, letting Maddox slip through the door could prove to be a very costly decision.?(EXCLUSIVE: MADDOX ON HIS BIG MATCH VS. RYBACK)
The damaged crane, part of construction on the One57 building, on West 57th Street (Allison Joyce/Getty Images??
Monday's giant storm inflicted the greatest damage on the lower half of New York City, but uptown, on West 57th Street, a massive, dangling crane is drawing crowds.
At a thousand feet above the ground, the 80-ton swing arm dangles next to the tallest condominium under construction in the city, located between 6th and 7th avenues. Bovis Lend Lease, the company managing the building's construction, is waiting for the last winds to die down before it scoops up the hanging hulk of metal.
"All I'm doing today is watching that crane," said a company employee, who asked not to be named. Wearing a muddied yellow raincoat, he leaned against a nearby shop on the corner of 56th Street, on standby.
"The only reason they haven't taken it down is because of the winds," he said. "Once they die down, they'll rig it up from the air. Right now it's no danger."
His remarks echoed the statement of the tower's developer, Gary Barnett, who told Crain's New York Business, "Everything that can be done is being done." In the meantime, metal gates and police tape block off access to the surrounding areas, as crowds of people stand along 57th Street and 5th Avenue taking photos and chattering as the crane's arm sways in the wind.
The crane is the most conspicuous damage up here resulting from the storm, but nearby, more destruction can be seen: On a building at the corner of Park Avenue and 59th Street, the facade of one floor about 20 stories up tumbled down during the storm, leaving a mass of debris on the now closed-off section below.
But for most who live around here, the most common word to describe the storm has been "boring." There have been few power outages, and the worst symptoms of the storm have been the gusts of wind. In nearby pubs like the Carriage House on 59th Street, people are hanging out, glancing at the images on TV of? more serious disorientation in lower Manhattan.
"It's honestly been a little boring," said Alana, who lives a few blocks away by the U.N. headquarters. She said she's chiefly been preoccupied with taking in her friend from Brooklyn, where winds were felt as early as Sunday night. "No power out, I've still got Internet. It hasn't been very exciting."
Others living uptown have also concentrated chiefly on coming to the aid of their friends, and checking on their work spaces downtown.
"I'm at a small tech company in Union Square, so I swung by to check on any leaking or flooding," says Brian, playing darts with a friend at the Carriage House. "Otherwise, it's mainly been working from home and helping out the people I know."
The White House is the best-known residence in the nation, and a few of its famous residents are rumored to be long-term tenants.
Ghost stories have been part of the executive mansion?s heritage for over a century, and as we approach Halloween, let?s take a look at the top stories passed down from people who claimed to have bumped into some departed presidents and others.
1. Lincoln?s ghost
There may have been more sightings of Abraham Lincoln?s spirit than presidents who inhabited the White House, and some reports seem to be in jest.
But there are a lot of reports from workers at the White House and even Winston Churchill that they bumped into Lincoln wandering the building years after his death.
Lincoln was shot at Ford?s Theater in 1865 and died at a nearby boarding house. But it is his spirit that is reportedly stuck at the White House, where he planned the Civil War and had started planning reconciliation when he was killed just days after Robert E. Lee?s surrender.
The most famous Lincoln story is from Churchill, who was staying at the residence after World War II, the British leader had just emerged from a bath, wearing nothing and smoking a cigar. He reportedly met the late president.
?Good evening, Mr. President. You seem to have me at a disadvantage,? Churchill allegedly said. He also refused to stay in the room after the encounter.
2. Jackson?s ghost
Another famous president who still could be seeking a longer term in the White House is Andrew Jackson.
The reported encounters with Old Hickory are not sightings but hearings. And what people reportedly hear from Jackson is a lot cursing from the 19th-century president.
One person who believed Jackson?s spirit remained in the White House was Mary Todd Lincoln, who held regular s?ances there after her son, Willie, died.
There was also a reported Jackson encounter during the administration of President Dwight Eisenhower.
3. Abigail Adams
John Adams? wife only stayed at the White House for a few months as its first occupant, along with her husband. Thomas Jefferson was the first president to spend a full term at the residence.
But some people believe Abigail Adams returns for an occasional visit to supervise the laundry.
Mrs. Adams used the East Room to hang out her laundry in 1800. A sighting of her was reported there during the Taft administration about 112 years later, when an apparition was seen carrying clothes in its arms. Recent Constitution Daily Stories
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4. Dolley Madison
The irrepressible Dolley Madison is best known today for rescuing the Gilbert Stuart painting of George Washington from the White House before the British burned it down during the War of 1812.
But in ghost lore, she?s best known for reportedly encountering two gardeners during the Wilson administration a century later.
First Lady Edith Wilson asked the two to move the fabled Rose Garden, which Madison had created and nurtured.
The gardeners were reportedly met by an angry Dolley.
Today, the Rose Garden remains where Dolley Madison wanted it.
5. The British fire starter
The most traumatic incident in White House history was its destruction by British troops in 1814. A royal soldier apparently died in the attack after he helped set fire to the White House, and there are reports he occasionally returns to finish the job.
One incident was reported a few years after the Truman-era restoration, where the spirit was seen trying to set a bed on fire.
Also, there was a major fire in the West Wing during the Hoover administration on Christmas Eve in 1929.
Officially, it was a clogged fireplace flue that stared the blaze.
Even today, recent White House staffers reported hearing strange noises late at night in the White House. But there?s one president who probably hasn?t come back for a guest appearance.
James Buchanan openly tired of being president as the Civil War grew near.
?If you are as happy in entering the White House as I shall feel on returning to Wheatland, you are a happy man indeed,? Buchanan said just before leaving office in 1861.
A 2004 satellite image provided by DigitalGlobe and the Institute for Science and International Security shows the military complex at Parchin, Iran, about 19 miles southeast of Tehran.
By Andrea Mitchell, NBC News
A senior administration official told NBC on Saturday that there have been backchannel talks between the U.S. and Iran about meeting bilaterally on the Iranians? nuclear program ? but that no meeting has been agreed to.
Expanding on a statement issued by the White House after The New York Times reported that there was an agreement, the official says that the backchannel talks have been done in full consultation with the allies ? the P5 + 1 and Israel.
The official pointed out that there have been bilateral talks in the past ? but that Iran refused to even meet with the P5 +1 during the recent United Nations meetings. He said the Iranians know there will be no agreement unless they give up their nuclear program.
Asked about the impact on Monday's foreign policy debate between President Barack Obama and Republican nominee Mitt Romney, the official said the administration is not happy that the story came out before the debate, but said the American people might be happy to know the administration is willing to explore all possibilities to get Iran to give up its nuclear program.
The Times, citing a senior administration official, said Iranian officials had insisted that the talks wait until after the presidential election so that they would know which president would be negotiating with them. The Times said: "Reports of the agreement have circulated among a small group of diplomats involved with Iran."
But in a statement Saturday evening, National Security Council spokesman Tommy Vietor said the U.S. and Iran had no such agreement:?
It's not true that the United States and Iran have agreed to one-on-one talks or any meeting after the American elections. We continue to work with the P-5+1 on a diplomatic solution and have said from the outset that we would be prepared to meet bilaterally. The President has made clear that he will prevent Iran from getting a nuclear weapon, and we will do what we must to achieve that. It has always been our goal for sanctions to pressure Iran to come in line with its obligations. The onus is on the Iranians to do so, otherwise they will continue to face crippling sanctions and increased pressure.
World powers accuse Iran of covertly using its uranium enrichment program to produce nuclear weapons. The Iranians insists the research and development is for projects to generate electricity and produce medical isotopes.
EU agrees on wider Iran sanctions
A six-country alliance of Western powers, including the United States, has been attempting to negotiate with the Iranians, with?occasional concessions by Iran and assertions that it?s willing to engage with the alliance. Despite the protracted dialogue,?diplomats hope that a negotiated settlement can be reached, with international sanctions providing an incentive.
In October 2009, the U.S and the Iranians agreed in Geneva that Iran would send its enriched uranium to Russia for safekeeping, in exchange for an agreement for enough nuclear fuel for its Tehran medical research reactor. However, the deal fell apart when Iran's negotiators returned home. Iranian officials told NBC News that their supreme leader, the Ayatollah Khomeini, told them they had gone beyond their instructions. That experience has made the White House wary of any agreement that is not blessed by the supreme leader, the sole authority over nuclear decisions in Iran.?
The sanctions began to bite this summer. Hyperinflation in Iran is pushing up prices daily and the dramatic slide in the value of the rial against the U.S. dollar led to unrest in Tehran earlier this month, when angry currency traders clashed with security forces.
The?European Union on Monday ratcheted up its sanctions,?prohibiting transactions between Iranian and European banks and banning imports of Iranian natural gas, among other measures.?
Netanyahu: Draw 'clear red line' to stop Iran
Israel, believed to have the Middle East's only atomic arsenal, sees a nuclear-armed Iran as a threat to its existence and has expressed frustration over the failure of diplomacy and sanctions to rein in Tehran. Western nations fear that a possible strike against Iran's facilities by Israel would lead to wider conflict.
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ScienceDaily (Oct. 19, 2012) ? A novel therapy that uses donated human stool to treat the deadly and contagious C.difficile infection is safe and highly effective, according to a Henry Ford Hospital study.
Researchers found that 43 of 49 patients recovered swiftly after treatment and had no adverse complications from C.diff three months later. Treatment is performed either through a nasogastric tube or colonscopy on an outpatient or inpatient basis.
Mayur Ramesh, M.D., a Henry Ford Infectious Diseases physician and senior author of the study, says the treatment, while appearing unconventional, has striking results.
"More than 90 percent of the patients in our study were cured of their C.diff infection," says Dr. Ramesh. "This treatment is a viable option for patients who are not responding to conventional treatment and who want to avoid surgery."
The study was presented October 19 at the annual Infectious Diseases Society of America meeting in San Diego.
In their study, researchers evaluated 49 patients who contracted Clostridium difficile, or C.diff, a germ that causes diarrhea and other intestinal problems and is linked to 14,000 deaths annually. Symptoms include water diarrhea, fever, loss of appetite, nausea and abdominal pain and tenderness. C.diff occurs in patients taking antibiotics, and can spread from person-to-person contact or from touching contaminated equipment and objects like door knobs.
Patients with a C.diff infection are typically treated with the antibiotics metronidazole or vancomycin. However, surgery could be required to remove the infected part of the intestines. In its study, Henry Ford treated patients between May 2010 and June 2012 with a therapy called intestinal microbiota transplantation (IMT), using donated stool from a healthy family member.
Dr. Ramesh says the healthy stool, when mixed with warm tap water and administered, helps to re-establish the normal intestinal flora in the patient's gastrointestinal tract. Intestinal flora is healthy bacteria that stimulates the immune system and aids the digestion and absorption of food.
"Patients who receive treatment through a nasogastric tube don't taste or smell the stool mixture as it's administered," Dr. Ramesh says. "Patients often resume their diet within a couple hours and are feeling better within 24 hours."
Of the 49 patients, 43 fully recovered, four died of causes unrelated to C.diff, one had intestinal surgery and one had no improvement.
The study was funded by Henry Ford Hospital.
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LONDON (Reuters) - Tens of thousands of British protesters marched through London on Saturday calling for an end to public spending cuts and tax rises launched by a government they accuse of elitism and ignorance about the plight of recession-hit voters.
Blowing horns and whistles, demonstrators streamed past the Houses of Parliament behind a banner declaring "Austerity is Failing", and called on Prime Minister David Cameron to do more to revive Britain's struggling economy.
The Conservative-led coalition is reeling from the resignation on Friday of a senior minister accused of calling police "plebs", a class-laden insult for working people, and the perception that they are out of touch.
"The wealthy don't realize the impact of the cuts and this government is only interested in what you can give them," said local government worker Eric Batty, 60, dressed in a black grim reaper cloak costume symbolizing death.
The government says it must stick to its plan to eliminate a budget deficit that stood at 8 percent of gross domestic product last year, the biggest of any major European country. It says the euro zone crisis has also cast a shadow over the British economy.
Cameron's party faced a barrage of negative headlines over the departure of Andrew Mitchell - the "Chief Whip" or party enforcer - four weeks after he swore at police guarding the gates to the prime minister's Downing Street office.
A separate row involving finance minister George Osborne, who sat in a first class train carriage with a standard class ticket before paying for an upgrade, added ammunition to critics who say the Conservatives are privileged and aloof.
Addressing protesters, opposition Labour leader Ed Miliband was quick to seize on the latest Conservative missteps to condemn Cameron's policies.
"He is a weak and clueless prime minister," Miliband told a cheering crowd. "Andrew Mitchell may have resigned but the culture of two nations runs right across this government. They cut taxes for millionaires and they raise taxes for ordinary families."
However, Miliband was booed when he told demonstrators that Labour would have had to make cuts too if it had won the last election, albeit at a slower pace.
Under grey autumnal skies, demonstrators waved banners saying "No Cuts", "Tax the Rich, Teach the Poor" and "Plebs of the World Unite", poking fun at Mitchell's resignation.
Nurses, cleaners, librarians and ambulance drivers were among those who joined the march and a rally in London's central Hyde Park, in one of the biggest anti-austerity protests this year. Organizers estimated that 150,000 people took part.
Marches also took place in Belfast, Northern Ireland, and Glasgow, Scotland.
"I've got friends who are in desperate straits, living in fear of losing their job and their house," said Nick Chaffey, 48, a Socialist Party campaigner married to a teacher who has taken a pay cut.
Police said the London march had passed peacefully and they expected to report a low number of arrests in a bulletin later.
COALITION UNDER PRESSURE
Trade union leaders are trying to use the rally to pile more pressure on Cameron, telling protesters the government's economic plan has failed and only prolonged Britain's recession.
"Austerity isn't working. It is hammering the poorest and the most vulnerable," said Brendan Barber, head of the Trades Union Congress, an umbrella group which represents 54 unions.
The coalition government had responded to calls from unions and the opposition Labour Party to do more to increase growth by relaxing planning laws and boosting lending to businesses.
Cameron's party staked its 2010 election campaign on the austerity program, calling for deeper cuts to welfare spending while dismissing the idea of a tax on the wealthy.
In an emergency budget announced after winning power, his coalition government said it would cut most departmental budgets by an average of around 20 percent over four years.
It announced a public sector pay freeze, set a new ceiling on the total state benefits any family can receive and cut tax relief on pensions. The VAT sales tax went up to 20 percent.
Conservative Party Chairman Grant Shapps said opposition Labour and the unions had "turned a blind eye" to the need to rein in spending.
He said: "By marching with them, Ed Miliband proved he still stands for more spending, more borrowing and more debt."
(Writing by Peter Griffiths; Additional reporting by Maria Golovnina and Michael Holden; Editing by Maria Golovnina and Rosalind Russell)
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MOSCOW, Oct. 19 ? Russia is set to launch five communication satellites in 2013, their producer?s chief designer said Friday.
?The first in line is Express-AM5. We will be ready to launch it in the second quarter of 2013,? Nikolai Testoyedov, head of the Informational Satellite Systems company, told the Interfax news agency.0 Express-AM5 will carry a Canadian-made telecommunications device, said Testoyedov, whose company is based in Krasnoyarsk region in Siberia.
The Express-AM6 satellites will also be ready at that time, he said, adding that financing for the launches has been arriving as scheduled.
Express-AM5 and Express-AM6 are designed for providing Russian territory with digital radio and TV broadcasting as well as for the government?s communications needs.
Three more satellites of that type, two of which will be launched in a bundle, have been scheduled for launch during 2013.
Russian Federal Space Agency Roscosmos has planned to upgrade Proton rocket carrier and Breeze booster for the upcoming launches of the Express-AM5 and Express-AM6 satellites.
Last Friday, Roscosmos announced a tender for the upgrades and said it would select a contract winner on Nov. 22.
In less than a month, the 2012 presidential election turned from an almost certain victory for President Obama to a neck-and-neck race. New York Times blogger and statistician Nate Silver and Princeton neuroscientist Sam Wang talk about making sense of the polls?and why not all votes are created equal.
The TV Club comments and recaps around the Web suggest that the premiere of American Horror Story: Asylum kept viewers up all night, if not with bad dreams, then definitely with nagging questions.
Both commenters and professional recappers agreed that the aliens?or at least what we think are aliens?that attacked Kit clash a bit with the tone of the rest of the show. Commenter ACslaterX called the alien thing ?strange? and offered this alternative theory: ?I thought for sure when we saw the flashing lights of the aliens as they probed Kit, it was going to flash back to the asylum while Kit was getting electroshock therapy ... but I guess it's just aliens; for now anyways.? I had a similar thought, though as Jenna Mullins pointed out over at E!, there?s still that pesky, Matrix-like neck implant to deal with.
A number of commenters reacted to our discussion of the muted (twisted?) streak of feminism running through the show via Sister Jude. Commenter TheDude disagreed with my reading of the ?don?t call yourself stupid? comment as a moment of sisterhood, pointing out rightly that Lange had ?just finished calling her stupid in the same scene, so I doubt she was linking arms in some kind of solidarity.? Wrote TheDude: ?She is the very definition of a sadist. Referring to her as a heroine is like referring to the lunatic doctor as a hero. She is a great character (so far), but has not been shown in any way to be a hero.?
Fair enough, Dude; I?ll admit that my unadulterated love of Jessica Lange may have clouded my judgment, but I still maintain that she?s a little more morally complicated that her collection of spanking implements would suggest.
The Internet also seems to agree with our dislike of the 2012 story starring Adam Levine and Jenna Dewan Tatum. Katy and I both found it unnecessary and boring, and Jen Chaney of the Washington Post echoed our feelings by rhetorically asking whether that whole scenario wasn?t just the worst. For those of you who agree with our wish to eliminate TheVoice host, I?ve got some good news and some bad news. In an interview with Entertainment Weekly, show creator Ryan Murphy noted that, while we?ll be spared the Leo and Teresa storyline in some episodes, the show will continue to explore 2012 Briarcliff via Levine?s smoldering eyes and remaining limbs for the rest of the season.
Speaking of actors, the EW interview contains a whole list of people, including Ian McShane, Frances Conroy, and Eric Stonestreet, who will be making appearances in future episodes, mimicking the trend of the first season in which ?Murder House? grew increasingly crowded as time went on. And! If you?re missing the dearly-departed Harmon family in the far less cozy confines of Briarcliff, news just broke yesterday that Dylan McDermott will be returning to the show with his ?blank virility? at some undisclosed point in the future. Something tells me Chlo? Sevigny?s nymphomaniac character will be all over that. ?
It's the latest snapshot of the growing burden of student debt and it's another discouraging one: Two-thirds of the national college class of 2011 finished school with loan debt, and those who borrowed walked off the graduation stage owing on average $26,600 ? up about 5 percent from the class before.
The latest figures are calculated in a report out Thursday by the California-based Institute for College Access and Success (TICAS) and likely underestimate the problem in some ways because they don't include most graduates of for-profit colleges, who typically borrow more than their counterparts elsewhere.
Still, while 2011 college graduates faced an unemployment rate of 8.8 percent in 2011, even those with debt remained generally better off than those without a degree. The report emphasized research showing that the economic returns on college degrees remain, in general, strong. It noted the unemployment rate for those with only a high school credential last year was 19.1 percent.
"In these tough times, a college degree is still your best bet for getting a job and decent pay," said TICAS President Lauren Asher. "But, as debt levels rise, fear of loans can prevent students from getting the education they need to succeed. Students and parents need to know that, even at similar looking schools, debt levels can be wildly different. And, if they do need to borrow to get through school, federal student loans, with options like income-based repayment, are the safest way to go."
The latest figures come at a time of increasing alarm about the sheer scope of student debt nationally, which by some measures has surpassed $1 trillion. Recent government figures show nearly 10 percent of borrowers of federal student loans in the most recently measured cohort had already defaulted within two years of starting repayment.
The issue has come up on the presidential campaign trail, though the candidates' specific plans haven't become a major issue. President Barack Obama has touted his record of ending $60 billion in subsidies to private lenders, directing the savings to student aid and implementing an income-based repayment plan that caps federal student loan payments at 15 percent of income and forgives repayment after 25 years.
Former Massachusetts Gov. Mitt Romney, his Republican challenger, argues the flood of federal student aid spending unleashed in recent years has led colleges to raise tuition prices. He wants to return to a system in which the government supports private lenders, arguing it's more cost-effective, and his campaign has called the income-based repayment program flawed.
In Tuesday night's second presidential debate, Romney repeated an assertion he'd made previously that "50 percent of kids coming out of college (are) not able to get work." That is not accurate, though twice earlier in the debate he made an important qualification, indicating he was referring to graduates who couldn't get "college-level jobs." Figures analyzed by Northeastern University's Center for Labor Market studies last spring did find 53.6 percent of bachelor's degree holders under age 25 were either unemployed or working in positions that don't fully use their skills or knowledge.
The latest TICAS report also cites studies that found more than one-third of recent graduates were in positions that did not require a degree, depressing wages, though other government figures cited by Georgetown University's Center on Education and the Workforce put the so-called "underemployment" rate for young college grads much lower ? at around 10 percent.
As for those who have no job at all, according to Georgetown the latest monthly unemployment figure for college graduates under age 24 is 10.5 percent (the figure typically jumps each spring as a new class graduates and declines over the course of the year; last March it was 5.4 percent).
"Increasing student debt in a weak economy can be a knock-out blow to many considering college," said Rich Williams, higher education advocate with U.S. Public Interest Research Group, which advocates for students. "As our economy is recovering, lawmakers must send every signal that college is a good investment. "
Among other finding in the TICAS report:
?Private (non-federal) student loans, which generally have weaker borrower protections but have been diminishing as a source of student borrowing, accounted for about one-fifth of the debt owed by the Class of 2011.
?Debt levels vary widely by state, ranging from $17,250 in Utah to $32,450 in New Hampshire.
?Debt at individual schools ranged from $3,000 to $55,250 though not all schools report that data.
?Among colleges, the percentage of graduates with debt ranged from 12 percent to 100 percent. At 64 schools, more than 90 percent of student graduated with debt.
___
Online: Companion interactive map with details for all 50 states, the District of Columbia, and more than 1,000 public and private nonprofit four-year colleges is available at www.projectonstudentdebt.org/state_by_state-data2012.php
___
Follow Justin Pope at http://www.twitter.com/JustinPopeAP
Some folks are petrified of admitting that they love writing about monsters. Especially literary writers (and yes, literary is a genre like any other, be it thriller or romance). As a teacher of creative writing, I find that some of my students (even in horror and dark fiction courses!) hide their love for the creepy, murderous, and undead from spouses, friends, and more ?literarily minded? writers like it?s a dirty little secret. ?Of course, I have spent valuable class time underscoring the importance of the monster in Western society, quoted Freud?s essays on the uncanny and Jung?s concept of the shadow self until I was blue in the face, but it?s all only theory (though fascinating theory) until one can understand the transformations that monsters can bring, the doors they can open, the power they can bestow.
Everyone needs a ?monster epiphany?: a realization of the physical and psychological spaces that monsters enable you to access, creepy corridors in your brain that can?t quite be reached any other way. ?And so, instead of quoting the fathers of modern psychology or cultural theorists, I turn, close to the eve of Halloween, to my own story of monsters to show just how crucial they can be to writers of all genres (whether you traffic in trolls or dabble in hell-hounds, or even?gasp!?grapple with the next great American novel) who are trying to own who they are and what they do.
~
When I was home sick from school, my grandmother would tuck me in front of the television, hand me a cup of steaming tea with some whiskey thrown in (Nana was Irish and according to her, alcohol cured nearly everything), and turn on the monsters. With feverish eyes, I devoured classics like Dracula and Frankenstein (or classics-by-then Hammer films starring Christopher Lee and Peter Cushing), ?and half-dreamt through Psycho, Pet Semetery, and The Night of the Living Dead. When the credits rolled and the evil (mostly) vaniquished, I always, always felt better.
To a little girl who had lived rough, been caught in the cycles of poverty, abuse, and abandonment and was forever afraid of being taken away, of being left behind, knowing and understanding the monsters in these movies became a manageable way for me to deal with the scary things in the world. They were the danger I could see, the danger I could easily banish with holy water, sunlight, a blow to the head, a crafty incantation. ?Knowing that they could be tamed, killed, and sometimes even appeased, helped me feel empowered, less scared of what lurked in the shadows of my own life.
By the time I was a teenager, monsters became like kin to me: they were the evil, strange, and just plain wrong, figures that could fight the conformist demons in the super-religious immigrant culture that I was trying to break away from. Monsters became my mirror, the metaphor of my dark desires, the true self that I feared giving voice to. They started whispering at the corners of notebooks until soon they screamed on the page in a voice that was never quite human but was always part me, part what I feared, and part what I yearned for. Submitting to these voices, these monsters, letting them speak through me became a way to explore the sinister parts of the human condition and the most powerful parts of myself. When I write monsters, I am truly owning all of my weird, dank, and strange passions, compulsions, desires, and fears.When I write monsters, I am no longer afraid.
What was your monster epiphany and how did it help you own what you write? Let me know in the comments!
About klpereira
KL Pereira likes to traipse around dark, woody crevices where most would rather not wander. Her fiction, poetry, and nonfiction has been published in Bitch Magazine, Clamor Magazine, Jabberwocky, The Medulla Review and other fine magazines, anthologies, chapbooks, and journals. She?s a member of two fabulous writing groups: the Ministry of Scrawl and the Cajun Sushi Hamsers From Hell. Currently, she is completing a collection of paranormal erotica (published under her fabulous and cheeky pen name) and a series of flash fiction fairy tales. Her website is: darknesslovescompany.com and you can chat with her about monsters anytime on Twitter (@kl_pereira).
(RNS) The "Nuns on the Bus" have been a consistently popular and effective faith-based tool for religious progressives this campaign season, but on Monday a group of demonstrators apparently organized by a local Tea Party affiliate met the nuns at a stop in Marietta, Ohio, and provided a far different welcome than the sisters usually receive.
Holding placards with slogans like "Bums on the Bus" and "Romney-Ryan Yes, Fake Nuns No," the protesters focused their fire on the abortion issue, accusing the sisters of not being sufficiently anti-abortion.
Someone claiming to be a member of the local "We the People" chapter -- that is the name used by some Tea Party affiliates in the region -- posted a YouTube video of the counter-demonstrators taken before the half dozen nuns and some 100 supporters arrived. It says there were more than 175 marchers opposing the nuns and it shows the demonstrators praying the rosary and singing hymns before challenging the sisters.
"What could be more innocuous, unless of course the nuns happen to be a group of radical, feminist ideologues whose previous political actions have been so out of step with the teaching of the Catholic Church that they have been condemned by the Vatican," the YouTube poster wrote in text accompanying the footage.
Sister Simone Campbell, who leads the Washington-based NETWORK, a left-leaning Catholic social justice group, has spearheaded the Nuns on the Bus tours and spoke against the budget drafted by GOP vice presidential nominee Paul Ryan during the Democratic National Convention in Charlotte, N.C.
The Nuns on the Bus have stressed social justice causes in their tours of areas hard-hit by the recession, and many conservative critics and political activists say their message shortchanges the abortion issue.
The sisters reject that criticism, and one of the nuns on the bus, Sister Monica McGloin (in photo), on Monday told the protesters in Marietta that "we are 100 percent pro-life."
"As many of your signs are showing, we believe life begins at conception and ends with natural death," McGloin said in remarks that were transcribed by Faith in Public Life, a liberal advocacy group that has provided media support for the sisters.
"And that we do not see focusing on one issue, one point of life, as a way that we should proceed. And that pro-life for us means that we do concern ourselves with living wage, just wage, access to healthcare, education, food, housing, care for our seniors, Medicare and other kinds of healthcare programs that are supportive. Providing daycare for children so their parents can work?"
"So we know from talking with people that what the people want is to continue to support the services that are helping us remain healthy, wholesome communities. So that?s what pro-life is."
"So what we?re hearing people say is that giving tax cuts to the very wealthy is not the way to go. Trickledown will not provide jobs. What we?re seeing is the real job creators are the sisters, the nuns, the people who operate in these not for profits, the people who operate in our local governments. They?re the ones that are doing the job creation. Not the wealthy -- who seem to be saving their money -- so they become wealthier."
McGloin directed the protesters to their only proposal, at FaithfulBudget.org, for "principles that should really undergird any budget we have. Because no matter who gets elected in November, we are going to need a budget."
Monday's confrontation came on the final day of a week-long tour by the Nuns on the Bus, at a morning stop near the local office of Republican congressman Bill Johnson.
The sisters had to be escorted through the protesters to reach Johnson's office, where they met with the congressman.
"Basically we wanted to talk to him about our trip ... and express the concerns that we've heard," McGloin told the Marietta Times. "People are really concerned about the notion that would give tax breaks to the wealthy while we're cutting funds that support programs that help people and communities."
USDA scientists collaborate with global researchers to advance the mapping of the barley genomePublic release date: 17-Oct-2012 [ | E-mail | Share ]
Contact: Mary Conley mary.conley@osec.usda.gov 202-720-1375 United States Department of Agriculture - Research, Education and Economics
WASHINGTON, October 17, 2012--In a major advance that will unlock the benefits of the mapping of the barley genome--one of the world's most important cereal crops--work conducted and supported by the U.S. Department of Agriculture (USDA) in collaboration with researchers around the world has resulted in the most advanced sequencing of the barley genome to date, as reported today in the journal Nature. The advance will give researchers the tools to produce higher yields, improve pest and disease resistance, and enhance nutritional value of barley. Past genomic research supported by USDA has provided similar benefits to crops such as tomato and corn, and helped improve cattle breeding and enhance the productivity of dairy cows.
"USDA supports innovative genomics research that is really moving us forward to meeting the many challenges we face in food, fuel and agriculture production," said Catherine Woteki, USDA's Chief Scientist and Under Secretary for Research, Education, and Economics. "This important step toward full barley genome sequencing offers enormous potential for global food security. Using the tools of genetics and genomics, we are keeping farmers profitable and our food supply safe and abundant."
Along with project investigators Timothy Close and Stefano Lonardi at the University of California, Riverside (UCR) and Gary Muehlbauer at the University of Minnesota, supported by grants from USDA's National Institute of Food and Agriculture (NIFA), USDA's Agricultural Research Service (ARS) scientists Roger Wise and Jesse Poland, together with scientists from 19 other organizations around the world, make up the International Barley Sequencing Consortium (IBSC).
Nearly twice as large as the human or maize genomes, the barley genome was a challenge to sequence, due to its complexity and its large proportion of repetitive regions, which are difficult to piece together into a true linear order. By developing and applying a series of innovative strategies that allowed them to circumvent these difficulties, the IBSC created a high-resolution assembly that places the majority of barley genes in order. This new resource provides the sequences of nearly all genes and associated regulatory regions, which will offer new direction to researchers seeking to improve barley yield and quality through functional genomics (determining the functions of important barley genes) and genomics-assisted breeding.
The work of IBSC highlighted in Nature provides a detailed overview of the functional portions of the barley genome, revealing the order and structure of most of its 32,000 genes and a detailed analysis of where and when genes are switched on in different tissues and at different stages of development. They describe the location of dynamic regions of the genome that carry genes conferring resistance to devastating diseases, such as powdery mildew, Fusarium head blight and rusts. This will provide a far better understanding of the crop's immune system. The achievement will also highlight with unprecedented detail the genetic differences among barley cultivars.
The success of the barley genome sequencing, and other grass family crops including wheat and rye, will allow breeders and scientists to effectively address the challenge of feeding the world's growing population living in an environment that increasingly challenges farmers and ranchers with extreme weather events.
###
The Nature paper can be found at: http://www.nature.com/nature/journal/vaop/ncurrent/full/nature11543.html.
For more information on the IBSC, please visit: www.barleygenome.org.
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AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
USDA scientists collaborate with global researchers to advance the mapping of the barley genomePublic release date: 17-Oct-2012 [ | E-mail | Share ]
Contact: Mary Conley mary.conley@osec.usda.gov 202-720-1375 United States Department of Agriculture - Research, Education and Economics
WASHINGTON, October 17, 2012--In a major advance that will unlock the benefits of the mapping of the barley genome--one of the world's most important cereal crops--work conducted and supported by the U.S. Department of Agriculture (USDA) in collaboration with researchers around the world has resulted in the most advanced sequencing of the barley genome to date, as reported today in the journal Nature. The advance will give researchers the tools to produce higher yields, improve pest and disease resistance, and enhance nutritional value of barley. Past genomic research supported by USDA has provided similar benefits to crops such as tomato and corn, and helped improve cattle breeding and enhance the productivity of dairy cows.
"USDA supports innovative genomics research that is really moving us forward to meeting the many challenges we face in food, fuel and agriculture production," said Catherine Woteki, USDA's Chief Scientist and Under Secretary for Research, Education, and Economics. "This important step toward full barley genome sequencing offers enormous potential for global food security. Using the tools of genetics and genomics, we are keeping farmers profitable and our food supply safe and abundant."
Along with project investigators Timothy Close and Stefano Lonardi at the University of California, Riverside (UCR) and Gary Muehlbauer at the University of Minnesota, supported by grants from USDA's National Institute of Food and Agriculture (NIFA), USDA's Agricultural Research Service (ARS) scientists Roger Wise and Jesse Poland, together with scientists from 19 other organizations around the world, make up the International Barley Sequencing Consortium (IBSC).
Nearly twice as large as the human or maize genomes, the barley genome was a challenge to sequence, due to its complexity and its large proportion of repetitive regions, which are difficult to piece together into a true linear order. By developing and applying a series of innovative strategies that allowed them to circumvent these difficulties, the IBSC created a high-resolution assembly that places the majority of barley genes in order. This new resource provides the sequences of nearly all genes and associated regulatory regions, which will offer new direction to researchers seeking to improve barley yield and quality through functional genomics (determining the functions of important barley genes) and genomics-assisted breeding.
The work of IBSC highlighted in Nature provides a detailed overview of the functional portions of the barley genome, revealing the order and structure of most of its 32,000 genes and a detailed analysis of where and when genes are switched on in different tissues and at different stages of development. They describe the location of dynamic regions of the genome that carry genes conferring resistance to devastating diseases, such as powdery mildew, Fusarium head blight and rusts. This will provide a far better understanding of the crop's immune system. The achievement will also highlight with unprecedented detail the genetic differences among barley cultivars.
The success of the barley genome sequencing, and other grass family crops including wheat and rye, will allow breeders and scientists to effectively address the challenge of feeding the world's growing population living in an environment that increasingly challenges farmers and ranchers with extreme weather events.
###
The Nature paper can be found at: http://www.nature.com/nature/journal/vaop/ncurrent/full/nature11543.html.
For more information on the IBSC, please visit: www.barleygenome.org.
[ | E-mail | Share ]
?
AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
Brad Maddox discusses his big match with Ryback next week: WWE.com Exclusive, Nov. 5, 20123MB comments on Drew McIntyre's whereabouts: WWE.com Exclusive, Nov. 5, 2012John Cena & Ryback vs. CM Punk & Dolph Ziggler: Raw, Nov. 5, 2012Brodus Clay vs. Wade Barrett: Raw, Nov. 5, 2012Jey Uso vs. Heath Slater: Raw, Nov. 5, 2012Kofi Kingston comments on being part of Team Foley: WWE.com Exclusive, Nov. 5, 2012WWE Official Rod Zapata comments on Brad Maddox: WWE.com Exclusive, Nov. 5, 2012 
Jessica Lange in American Horror Story 
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Public release date: 17-Oct-2012
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